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| Hamartoma (Chondrofibrolipoma) |
| Etiology: • Unknown. • Although previously called hamartoma, these lesions develop over years and are not congenital. |
| Pathogenesis: • Unknown |
| Epidemiology: • Patients over 40; women outnumber men 2:1 • Rare cause of solitary lesion detected on radiographic studies |
| General Gross Description: • Solitary nodule or 3coin lesion2 • May be firm and glassy depending on the amount cartilage within the lesion |
| General Microscopic Description: • Composed of mature cartilage,fibrous tissue and fat as well as occasional blood vessels and respiratory epithelium. |
| Clinical Correlations: • Often found on chest xray or other radiographic study and diagnosed as part of an evaluation to rule out carcinoma. |
| References: • Cotran RS, Kumar V, Robbins SL. Robbins Pathologic Basis of Disease. 5th edition. W.B. Saunders. Philadelphia 1994. pp.727. |