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Adenomatoid Malformation of Lung

Etiology: • Congenital.

Pathogenesis: • Abnormal bronchiolar division resulting in cyst formation.

Epidemiology: • Rare congenital anomaly • Type 2 may be associated with other malformations.

General Gross Description: • Three major patterns including I (large cysts), II (multiple small-medium cysts), III (massive area of small cysts)

General Microscopic Description: • Type 1 generally lined by ciliated epithelium. • Type 2 and 3 lined by bronchiolar type epithelium

Clinical Correlations: • Present in post-natal period with respiratory distress. • Patients with type 2 lesion may have symptoms from other malformations.

References: • Saldana MJ. Pathology of Pulmonary Disease. J.B. Lippincott. Philadelphia 1994, pp. 79-81.