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| Kypho-scoliosis |
| Etiology: • Scoliosis can be caused by bad posture, muscle spasms, or psychogenic factors. • Rarely, metabolic disorders, such as Prader-Willi syndrome could result in scoliosis. • Most cases of scoliosis are idiopathic. • Idiopathic scoliosis appears to have a genetic predisposition. |
| Pathogenesis: • Pathogenesis: Extreme disorders in spine curves could result in problems in both respiratory and cardiovascular function. |
| Epidemiology: • Some degree of spinal deformity occurs in about 5% of children. • More common in females. |
| General Gross Description: • The spine is normally straight in the coronal plane. • In the sagital plane, there is normally is kyphosis in the thoracic area and lordosis in the cervical and lumbar areas. • Abnormal curvature, side-to-side, is referred to as scoliosis. • Abnormal curvature in the sagital plane is referred to kyphosis. |
| General Microscopic Description: • There is no specific histological alteration in kyphosis or scoliosis. |
| Clinical Correlations: • Some cases of idiopathic scoliosis are assocciated with other congenital malformations, particularly of the kidneys. • Extreme kyphosis in the thoracic area reduces the space available to viscera restricting both the lung capacity and venous return to the heart. |
| References: Principles and Practice of Pediatrics. F.A. Oski, Editor in Chief. II Edition. J.B.Lippincott. pp 1034. |