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Intraductal Papilloma

Etiology: • Unknown

Pathogenesis: • Unknown.

Epidemiology: • Responsible for up to 1/2 of abnormal nipple discharge

General Gross Description: • Usually in major nipple duct, close to nipple • Usually < 1 cm. in size

General Microscopic Description: • Multiple papillae with fibrovascular cores • Cells overlying papillae resemble normal duct epithelial cells • Myoepithelial cells also present

Clinical Correlations: • Bloody nipple discharge or small subareolar mass • Will recur if duct system not excised

References: • Cotran RS, Kumar V, Robbins SL. Robbins Pathologic Basis of Disease 5th edition. W.B. Saunders, Philadelphia, 1994, p.1099