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Tubular Carcinoma

Etiology: • Unknown

Pathogenesis: • Unknown; see general discussion of duct carcinoma

Epidemiology: • Represents xy5

General Gross Description: • Usually small (• Stellate

General Microscopic Description: • Small duct-like structures lined by a single cell layer often with an angular profile on cut section • Embedded in stroma with increased cellularity and/or collagen and elastin • Nuclei are generally very bland and closely resemble normal breast duct epithelium • May be difficult to separate from sclerosing adenosis or radial scar but generally spread outside the confines of enlarged lobules

Clinical Correlations: • Diagnosis made when 75% of neoplasm in tubular • Prognosis is excellent

References: • Rosen PP, Oberman H. Tumors of the Mammary Gland. AFIP, Washington, 1993, pp. 175-181