Normal Sebaceous Gland
Normal Sebaceous Gland

A normal sebaceous gland under high power.
Towards the periphery of this single acinus of a sebaceous gland is a single layer of cuboidal cells that are somewhat deeper staining.
Towards the center are large cells which are pale staining cytoplasm and a central pyknotic nucleus.
At the very center is a dark staining structure that represents the duct of this gland.
The central, light-staining cells are normally shed as such into the hair shaft and form the oily secretion that coats the hair as well as the overlying skin.
(Description By:T.V. Rajan, M.D. )
(Image Contrib. by:T.V. Rajan, M.D. UCHC )