Hodgkins Disease - Nodular Sclerosis

Hodgkins Disease - Nodular Sclerosis •Low power view of a field from a lymph node with Hodgkins disease. •Towards the center of this field is a large bi-nucleate cell with prominent nucleoli. •This is a characteristic Reed-Sternberg cell. •The characteristic features in this field, aside from the Reed-Sternberg cell, include the lack of defined lymph node architecture and the presence predominantly of lymphocytes. (Description By:T.V.Rajan, M.D. ) (Image Contrib. by:T.V.Rajan, M.D. UCHC )