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Atrophy, Brain
Cerebral Atrophy

•One half of a coronal section of the brain at the level of the lenticular nucleus and internal capsule resting on its side
•Note the marked widening of the sulci and narrowing of the gyri and markedly enlarged lateral ventricle
•This is a case of severe atrophy due to Battens disease, a ceroid-lipofuscinosis which produces what is known as hydrocepholus ex vacuo; that is, enlarged ventricles due to loss of parenchymal tissue.
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Etiology, Pathogenesis, Clinical, and More Info