| Ulcers
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Etiology
• Mechanical pressure
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Pathogenesis
• Erosion by pressure,
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Epidemiology
• Patients intubated for more than 24 hours
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General Gross Description
• Ulcers with
hemorrhagic rim and red tan base
• Frequently located just below the vocal cords and anteriorly along each
cartilaginous ring
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General Microscopic Description
• Necrotic debris and neutrophils on surface
• Reactive squamous epithelium with prominent nucleoli in large nuclei
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Clinical Correlation
• Will heal completely if patient survives to extubation
• Long term intubation may lead to squamous metaplasia with atypia
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References
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th edition. Philadelphia, W.B. Saunders, 1994, pp. 744.
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| Ulcers
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| Synopsis by: Melinda Sanders M.D. (T24100M38000)[137]
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