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Cystic Adenomatoid Malformation
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Cystic Adenomatoid Malformation

Lower lobe of lung.
Black arrow points to large cyst; yellow areas to smaller cysts.
White arrows highlight pleural surface.
Portion of lung adjacent to pleura has normal apearance; remainder shows enlarged spaces.
(Description By:Melinda Sanders, M.D. )
(Image Contrib. by: UCHC )
Adenomatoid Malformation
Etiology

Congenital.
Pathogenesis

Abnormal bronchiolar division resulting in cyst formation.,
Epidemiology

Rare congenital anomaly
Type 2 may be associated with other malformations.
General Gross Description

Three major patterns including I (large cysts), II (multiple small-medium cysts), III (massive area of small cysts)
General Microscopic Description

Type 1 generally lined by ciliated epithelium.
Type 2 and 3 lined by bronchiolar type epithelium
Clinical Correlation

Present in post-natal period with respiratory distress.
Patients with type 2 lesion may have symptoms from other malformations.
References

Saldana MJ. Pathology of Pulmonary Disease. Philadelphia: J.B. Lippincott, 1994. pp. 79-81.
Adenomatoid Malformation
Synopsis by: Melinda Sanders M.D. (T28000M20000)[134]
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