Squamous Carcinoma of Lung (High Power)

Squamous Carcinoma of Lung (High Power) • This high power view centers on a neoplastic group of squamous cells. • The cell indicated with the yellow arrow is a large squamous cell with a prominent nucleolus and abundant cytoplasm. • Other cells show much darker hyperchromasia of the nucleus, often with irregular nuclear outlines. • The red arrows point to intercellular bridges, caused by the retraction of the cytoplasm with fixation. • The intercellular bridges are formed by desmosomes. • The presence of bridges permits the categorization of non-keratinizing lesions as squamous. (Description By:Linda Ernst ) (Image Contrib. by:Linda Ernst UCHC )