| Angiofibroma
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Etiology
• Unknown
• Increases in size under the influence of testosterone
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Pathogenesis
• Unknown,
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Epidemiology
• Predilection for teenage boys (peak incidence at age 15)
• Rarely ever seen in girls, if at all
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General Gross Description
• Firm, fibrous masses
• Well circumscribed
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General Microscopic Description
• Numerous vascular spaces embedded in stroma which is collagenized
• Spaces generally lined by single layer of endothelium
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Clinical Correlation
• Present with nasal obstruction and bleeding, as arise from lateral nasopharynx
• May bleed profusely with surgery, which is treatment of choice
• May need chemotherapy if surgery cannot remove intracranial extension
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References
• Sternberg SS ed. Diagnostic Surgical Pathology, 2d edition, Lippincott-Raven; Philadelphia. 1996, pp. 874-5.
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| Angiofibroma
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| Synopsis by: Melinda Sanders M.D. (T21000M91600)[434]
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