Metastatic Adenocarcinoma

Metastatic Adenocarcinoma •Cross section of a spleen showing a single focus of a metastatic adenocarcinoma: •Notice the replacement of the normal, darkly dark-red, splenic parenchyma by a deposit of a uniformly tan-gray nodule of tissue. •Splenic metastases, from malignancies elsewhere, are not common. •This phenomenon has been attributed to the elevated expression of fas ligand by splenic parenchyma. (Description By:T. V. Rajan, M.D. ) (Image Contrib. by:Saint Francis Hospital Saint Francis Hospital )