Spleen with Sickle Cell Disease

Spleen with Sickle Cell Disease •A small multiply infarcted spleen in a case of a patient with sickle cell anemia: •Notice the extremely distorted external appearance of this spleen, with multiple, depressed scars. •The normal slate gray appearance of this spleen in visualized in the areas between the depressed scars. •Significant reduction of splenic size is common in patients with sickle cell anemia and is referred to auto-amputation. (Description By:T.V.Rajan, M.D. ) (Image Contrib. by:Melinda Sanders, M.D. UCHC )