Spleen with Sickle Cell Disease

Spleen with Sickle Cell Disease •The remaining spleen in a case of a patient with sickle cell anemia. •Notice that in contrast to a normal spleen, which is a large structure weighing approximately 150 grams, a very small remnant of splenic tissue is seen in this patient. •Multiple splenic infarcts, resulting in a small spleen, are common in this disease and are referred to as auto-amputation. (Description By:T.V.Rajan, M.D. ) (Image Contrib. by:Melinda Sanders, M.D. UCHC )