Normal Spleen

Normal Spleen •A high power view of normal spleen focusing on the white pulp. •The yellow arrow points to an arteriole surrounded by a cuff of lymphocytes. •Notice the typically eccentric arrangement of these lymphocytes. •Most of the lymphocytes in this area are probably T lymphocytes. •When a germinal center occurs within the white pulp, it tends to be placed even more eccentrically, with a typical central germinal center surrounded by a cuff of resting B lymphocytes. (Description By:T.V. Rajan, M.D. ) (Image Contrib. by:T.V. Rajan, M.D. UCHC )