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| Ectopic pregnancy |
| Etiology •Associated with previous tubal damage from •endometriosis •surgery •pelvic inflammatory disease |
| Pathogenesis •damage to fallopian tube which may be mechanical or functional, |
| Epidemiology •Reproductive age women •History of sexually transmitted disease •History of endometriosis |
| General Gross Description •dilated, congested fallopian tube with or without rupture site •lumen filled with soft, tan hemorrhagic villi and occasionally with recognizable amnionic sac with embryo •lumen also containing blood clot |
| General Microscopic Description •lumen contains chorionic villi of first trimester type with complete layer of cytotrophoblast and syncytiotrophoblast surrounding stroma containing vessels with nucleated erythrocytes •implantation site in tubal wall with converting decidual vessels |
| Clinical Correlation •patients may have typical signs of pregnancy until approximately 8 weeks of gestation •develop acute abdomen with shock from hemorrhage into the peritoneal cavity •surgical emergency •can remove entire tube or simply contents with repair |
| References • Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1079 |
| Ectopic pregnancy |
| Synopsis by: Melinda Sanders M.D. (T86100F31100)[4] |
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