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Normal Membranes (20X)
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Normal Membranes (20X)

The amnion is tall and columnar with round nuclei and eosinophilic cytoplasm.
This epithelium is typical of late pregnancy.
The amniotic mesoderm is acellular and collagenous.
(Description By:Linda Ernst )
(Image Contrib. by:Linda Ernst UCHC )
Normal Membranes
Etiology

Not applicable
Pathogenesis

Not applicable,
Epidemiology

Not applicable
General Gross Description

Normally translucent gray and shiny
General Microscopic Description

Layer of amnionic epithelium with associated connective tissue termed mesoderm; derived from fetal ectoderm
Separates readily (since it is held there by pressure of amniotic fluid) from underlying chorionic mesoderm which includes residual extravillous trophoblast, avascularized atretic villous remnants (chorion laeve) and decidualized endometrial stromal cells
Maternal vessels (unoconverted spiral arteries) provide blood flow
Formation of membranes occurs between 3rd week post conception and 16 week
Clinical Correlation

Not applicable
References

Benirschke K, Kaufmann P. Pathology of the human placenta, 3rd ed. New York: Springer-Verlag, 1995, pp. 268-271.
Normal Membranes
Synopsis by: Melinda Sanders M.D. (T88200M00100)[428]
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