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| Fibroma-Thecoma |
| Etiology • unknown |
| Pathogenesis • unknown, |
| Epidemiology • rare neoplasm |
| General Gross Description • smooth external surface • firm, tan white interior with interlacing bundles of fibers • very large neoplasms may have cystic spaces |
| General Microscopic Description • bland, spindle cells resembling fibroblasts • some collagen production • occasional lipid laden thecal cells may be seen |
| Clinical Correlation • reproductive age or perimenopausal • 40% show associated ascites (Meig's syndrome) clinically similar to ovarian adenocarcinoma • ascites disappears with removal of the primary • may be associated with basal cell nevus syndrome • rare malignancy termed fibrosarcoma |
| References • Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1075-6 |
| Fibroma-Thecoma |
| Synopsis by: Melinda Sanders M.D. (T87000M88100)[51] |
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