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| Normal Ovary |
| Etiology • Not applicable. |
| Pathogenesis • Not applicable , |
| Epidemiology • Not applicable |
| General Gross Description • Measure 2-5 x 1.5-3.0 x 0.5 -1.5 cms. • Weigh 8 grams • Attached by mesovarium to posterior broad ligament, by utero-ovarian ligament to the uterine cornu, and by the infundibulopelvic ligament to the lateral pelvic walls • Smooth external surface of prepubertal ovary becomes convoluted and scarred with age • Cut surfaces show ill defined outer cortex and inner medulla • Vividly yellow corpus luteum; white irregular corpora albicans • Vascular supply derives from ovarian artery and ascending branch of the uterine artery • Venous drainage into the ovarian veins • Lymphatic drainage parallels ovarian vessels |
| General Microscopic Description • Covered by focally pseudostratified epithelium often difficult to see • Stroma of spindly fibroblast-like cells and may contain luteinized cells, decidualized cells, smooth muscle cells, and neuroendorine cells • Granulosa cells formed by birth with no lipid content until just prior to ovulation • Call-Exner bodies (cavities in the graulosa cell layer) contain basal lamina • Theca cells derive from stroma • Ova are present in follicles • Post-ovulation mass of yellow luteinized cells forms corpus luteum • Scarring of corpus luteum results in fibrotic corpous albicantia. |
| Clinical Correlation • Not applicable |
| References • Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1034 |
| Normal Ovary |
| Synopsis by: Melinda Sanders M.D. (T87000M00100)[257] |
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