| Seminoma
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Etiology
•Unknown.
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Pathogenesis
•Unknown.
•Seminomas are germ cell neoplasms.,
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Epidemiology
•Males.
•Peak incidence in the fourth decade of life.
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General Gross Description
•On cut section, the tumor is usually gray-white, homogenous and
lobular.
•Necrosis and hemorrhage are inconspicuous in small tumors and
more notable in larger tumors.
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General Microscopic Description
•Typical seminoma is composed of monotonous sheets of uniform round cells
with rather clear cytoplasm and centrally located round nuclei with prominent
nucleoli.
•The stroma frequently shows lymphocytes,
•Granulomatous
inflammatory foci can be present.
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Clinical Correlation
•Unilateral non-painful testicular enlargement.
•Seminoma occur most
frequently in the fourth and fifth decade of life.
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References
•
• Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1016-1017.
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| Seminoma
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| Synopsis by: Harold Yamase M.D. (T78000M90613)[237]
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