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Acute Vasomotor Nephropathy
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Acute Vasomotor Nephropathy

The vessels of the medulla are markedly congested and show many nucleated blood cells.
This vascular congestion relates to the dark color of the medulla in gross specimens.
(Description By:H. Yamase, M.D. )
(Image Contrib. by:H. Yamase, M.D. UCHC )
Acute Vasomotor Nephropathy
Etiology

Inadequate blood flow to both kidneys (shock).
Pathogenesis

The reduction in blood flow is inadequate to maintain renal function and yet not complete and sustained enough to cause infarction.
The condition is reversible.,
Epidemiology

Frequent complication of shock.
General Gross Description

The renal cortex is pale and the medulla is dark and congested.
General Microscopic Description

The tubular epithelium, especially of the proximal tubules undergoes necrosis and sloughs into the tubular lumens. These cells degenerate into amorphous clumps sometimes seen in more distal portions of the nephron as granular pigmented casts.
The vasa recta are congested and accumulate increased numbers of white cells.
Clinical Correlation

Acute renal failure.
References

Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 964-967.
Acute Vasomotor Nephropathy
Synopsis by: Harold Yamase M.D. (T71000M53150)[184]
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