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| Normal Esophagus |
| Etiology • Not applicable. |
| Pathogenesis • Not applicable., |
| Epidemiology • Not applicable. |
| General Gross Description • Extends from cricoid cartilage in the posterior mediastinum through the diaphragm to join the stomach • Endoscopic distance measured from the incisors to the GE junction varies from 38-43 cms. • Supplied by inferior thyroid artery, bronchial arteries, intercostals and aorta, as well as left gastric and inferior phrenic arteries • Drains into azygous system in upper 2/3; some portal drainage for distal esophagus |
| General Microscopic Description • Non-keratinizing stratified squamous mucosa • Basal layer normally 10-15% of thickeness • Scattered intraepithelial lymphocytes and Langerhans cells are seen • Lamina propria which may contain mucus secreting glands lies on muscularis mucosae • Submucosa contains submucosal glands overlying muscularis propria and then delicate fascia. |
| Clinical Correlation • Not applicable. |
| References • Histology for Pathologists. Sternberg SS ed. New York: Raven Press, 1992. pp. 516-527. |
| Normal Esophagus |
| Synopsis by: Melinda Sanders M.D. (T62000M00100)[542] |
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