Adenocarcinoma of Colon

Adenocarcinoma of Colon •The depressed central region of this raised tumor is the gross evidence that the original benign polyp has transformed to a carcinoma. The ulcerated center represents necrotic tumor. •The smooth raised pink-white tissue surrounding the ulcerated tumor is viable tumor. •The lobulated edge (arrow) represents residual component of the adenomatous polyp in which this lesion originated. •The lesion is typically sharply demarcated from the adjoining normal mucosa. (Description By:Martin Nadel, M.D. ) (Image Contrib. by: UCHC )