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Normal Artery
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Normal Artery

Higher power of previous view showing a layer of endothelial cells lining the lumen
The dark, red, wavy line is the elastica interna.
The intima consists of the endothelial cells and the very thin space between them and the internal elastic lamina.
It is more substantial in arteries from adults.
Note the elongate parallel nuclei of the smooth muscle in the media.
(Description By:T.V. Rajan, M.D. )
(Image Contrib. by:T.V. Rajan, M.D. UCHC )
Normal
Etiology

N.A.
Pathogenesis

N.A.,
Epidemiology

N.A.
General Gross Description

Yellow white vessels with elastic walls.
General Microscopic Description

Large and small arteries, <1cm in diameter have 3 layers, intima, media, and adventitia.
Intima is thin and includes the endothelium, an underlying thin layer of connective tissue containing smooth muscle. An elastic fiber layer, the elastica interna, demarcates the intima from the media.
Media is thickest layer and is made up of smooth muscle and collagen fibers. Larger arteries may contain some elastic fibers.
Adventitia is sharply demarcated from the smooth muscular media, and is a thin layer containing elastic fibers in an loose connective tissue.
Clinical Correlation

N.A.
References

Burkitt G etal. Wheater's basic histopathology, 3rd ed. New York: Churchill Livingstone, 1996.
Normal
Synopsis by: J. Hasson, MD (T41000M00100)[571]
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