Medium power view of normal adipose tissue - for comparison with a liposarcoma
Medium power view of normal adipose tissue - for comparison with a liposarcoma

A medium power view of normal adipocytes.
Notice the typically polygonal appearance of a single adipocyte, encircled by the many green arrows.
Adipocytes normally look empty because most of their structure is composed of a single large globule of fat that is extracted by the fixation, embedding and sectioning processes.
The only structure that is visualized in standard H&E staining is a thin rim of cytoplasm that lies just beyond the tips of the green pointers.
Embedded within this thin rim of cytoplasm is a highly condensed, uniformly dense staining nucleus.
Two typical adipocyte nuclei are indicated at the tips of the black pointers.
(Description By:T.V.Rajan, M.D. )
(Image Contrib. by:T.V.Rajan, M.D. UCHC )