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Synovial Hyperplasia
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Synovial Hyperplasia

High power view of a papillary-like growth of synovium in a case of synovial hyperplasia.
This image clearly demonstrates the central fibrovascular core of the papillary projections.
The four space-like lesions containing red blood cells are vascular channels.
The pink whorled material represents the collagen and the elongated nuclei within this red swirling material are fibroblast nuclei.
To the left of this image are the deeply staining columnar to cuboidal cells that represent the synovial epithelium.
(Description By:T.V. Rajan, M.D. )
(Image Contrib. by:T.V. Rajan, M.D. UCHC )
Synovial Hyperplasia
Etiology

Associated with any irritant within the joint (torn cartilage, chipped bone).
Associated with inflammatory process including such disorders as rheumatoid arthritis.
Pathogenesis

Epithelial hyperplasia in response to injury.
Inflammation or mechanical trauma may cause the injury.,
Epidemiology

Frequent.
Epidemiology that of injury to joints and of arthritic diseases.
General Gross Description

Congested, thickened, granular synovium.
General Microscopic Description

Multiple layers of synovium.
May be associated with inflammation, foreign material, hemorrhage, and/or scar.
Clinical Correlation

Non specific finding associated with injury.
References

Cotran RS, Kumar V, Robbins SL: Robbins Pathologic Basis of Disease. 5th ed. Philadelphia, W.B. Saunders, 1994, pp. 1250-9.
Synovial Hyperplasia
Synopsis by: Melinda Sanders M.D. (T12040M72000)[614]
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